Bicoid by the Numbers: Quantifying a Morphogen Gradient
نویسنده
چکیده
Morphogen gradients are typically analyzed from static images of fixed embryonic tissues. Two papers in this issue of Cell now report live imaging of the Bicoid gradient in developing fruit fly embryos (Gregor et al., 2007a, 2007b). Their findings indicate that the gradient is highly reproducible from embryo to embryo and reveal that the nuclear dynamics of Bicoid are critical for maintaining precision within the gradient.
منابع مشابه
Pre-Steady-State Decoding of the Bicoid Morphogen Gradient
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BACKGROUND During development, embryos decode maternal morphogen inputs into highly precise zygotic gene expression. The discovery of the morphogen Bicoid and its profound effect on developmental programming in the Drosophila embryo has been a cornerstone in understanding the decoding of maternal inputs. Bicoid has been described as a classical morphogen that forms a concentration gradient alon...
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عنوان ژورنال:
- Cell
دوره 130 شماره
صفحات -
تاریخ انتشار 2007